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Week 48 What you may notice: Clear improvements in body composition

If transitioning from subcutaneous to nasal administration, start at your established injectable dose and adjust based on response rather than assuming a specific conversion ratio

Any cloudiness or visible debris indicates contamination or degradation

The open question for regulators conducting the CagriSema FDA review is whether combining two appetite-suppressing mechanisms produces an additive gastrointestinal burden that alters the benefit-risk calculation in a market already offering several tolerable alternatives

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