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The new label for Ozempic is based on the results of the FLOW trial, which showed a statistically significant reduction in kidney disease progression, as well as cardiovascular and kidney death with a 1 mg/kg weekly dose of the injectable drug compared to placebo

These trials enrolled thousands of reproductive-age women over 68 weeks, providing robust real-world safety data

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However, recent evidence suggests further pathophysiological mechanisms for this side effect

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