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Diagnosis requires colonoscopy with mucosal biopsies demonstrating characteristic histologic features: continuous inflammation limited to the mucosa and submucosa, crypt architectural distortion, and increased inflammatory cells
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Researchers comparing subcutaneous vs intramuscular peptide injection routes consistently find that IM delivery yields faster peak plasma concentrations due to the high capillary density in muscle tissue
doi: 10.1093/humupd/dmae034
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