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Injectable B12 has few direct drug interactions, but certain medications can interfere with B12 absorption or measurement: Chloramphenicol: This antibiotic may antagonise the haematological response to B12 in some patients, potentially preventing the expected rise in red blood cell count

Injections bypass the digestive system and provide immediate, high-dose absorption

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Vitamin B1 (thiamine) functions as a coenzyme with the transketolase enzyme in the pentose phosphate pathway of glycolysis

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