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SGLT-2 Inhibitors as Cardio-Renal Protective Agents
Fumaric acid esters Fumaric acid esters are the most investigated NRF2 activators
Additional modifications were produced to improve the original discovery, of which four emerged as most logical candidates for drug development, including GHRP-6 (His-D-Trp-Ala-Trp-D-Phe-Lys-NH 2 ), Hexarelin (His-D-Mrp-Ala-Trp-D-Phe- Lys-NH 2 ), GHRP-2 (D-Ala-D--Nal-Ala-Trp-D-Phe-Lys) or pralmorelin which was most potent, and ipamorelin (Aib-His- D-2-Nal-D-Phe-Lys-NH 2 ) which persisted in the circulation longer than the other GHRPs 3
Cureus , 17(1), e78045
Matsuzaki T, Sasaki K, Tanizaki Y, Hata J, Fujimi K, Matsui Y, et al
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