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Dose-by-dose weight loss in Phase 2 (NEJM) Phase 2 NEJM weight loss by dose, 24 and 48 weeks Dose 1 mg 24 weeks -7.2% 48 weeks -8.7% Dose 4 mg 24 weeks -12.9% 48 weeks -17.5% Dose 8 mg 24 weeks -15.7% 48 weeks -22.8% Dose 12 mg 24 weeks -17.5% 48 weeks -24.2% Dose Placebo 24 weeks -1.6% 48 weeks -2.1% Source: Jastreboff et al., NEJM 2023
GLP-1 receptor agonist medications developed originally for diabetes and later established as transformative treatments for obesity appear to do something to that state
At maintenance weight Once you reach your target weight and transition to a maintenance protocol , your available subcutaneous tissue may be noticeably less than when you started
Vitamin B12, on the other hand, is involved in the production of red blood cells, the maintenance of a healthy nervous system, and in the normal metabolism of proteins, fats, and carbohydrates
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