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NPY neurons, also known to express AgRP, were inhibited by semaglutide, suggesting disinhibition of AgRP signaling to the PB, resulting in increased activation of this nucleus
Nutritional Deficiencies The mechanism that makes GLP-1 medications effective, slowing digestion and reducing food intake, can also lead to significant nutritional gaps: Many patients consume fewer calories, making it difficult to obtain adequate nutrients Altered digestive processes may reduce the efficiency of nutrient absorption Key nutrients at risk include calcium, vitamin D, B vitamins, iron, and protein 4
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