By Lana Pine | Published on September 16, 2025 4 min read Overall, GLP-1 receptor agonists (GLP-1 RAs) appear to be effective and relatively safe for kids and teens, at least in the short term, in helping with blood sugar control, weight and heart-related health risks, according to a new study published in JAMA Pediatrics
(7) Noordam R, Gunn DA, Tomlin CC, Maier AB, Griffiths T, Catt SD, Ogden S, Slagboom PE, Westendorp RG, Griffiths CE, van Heemst D, de Craen AJ
The response is highly individual and short-lived during and after meals
Currently, research on GLP-1 agonists during pregnancy is limited, and most guidelines recommend against their use while pregnant due to potential unknown effects on fetal development
This dual approach allows for broader analysis of pathway behavior in controlled experimental settings