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FIGURE 3 3.1 Inducing Factors of Ferroptosis 3.1.1 Iron (Fe 2+ ) Metabolism As an indispensable cofactor in many enzyme metabolism processes and a catalyst of redox-cycling reaction (Stoyanovsky et al., 2019), iron is involved in a variety of important physiological and biochemical processes in vivo

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We demonstrated that GSTM2 suppressed the progression of hepatic steatosis by inhibiting ASK1-p38/JNK signalling

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