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(2019) suggested that the serum TMAO levels were positively correlated with the serum total bile acids concentrations, particularly the percentage of taurocholic acid (a farnesoid X receptor (FXR) antagonist bile acid), resulting in increased expression of bile acid synthesis enzyme CYP7A1 (cholesterol 7-hydroxylase) in NAFLD patients
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Owens C W I, Belcher R V
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