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Certain populations face higher deficiency risk: vegetarians and vegans (B12 is primarily found in animal products), adults over 50 (decreased stomach acid reduces B12 absorption), individuals with digestive disorders like Crohn's disease or celiac disease, and those taking medications like metformin or proton pump inhibitors

Higher doses do not always produce better results

Peptides used in weight management are typically administered via subcutaneous injection and prescribed under medical supervision

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Mechanism studied: NNMT catalyses the methylation of nicotinamide