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Once SAM donates a methyl group it becomes S-adenosylhomocysteine (SAH), which is then metabolized to homocysteine

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Pfalzer et al., 2022)

OS significantly impairs male fertility through disruption of sperm capacitation, induction of DNA damage such as sperm DNA fragmentation (SDF), reduced motility, and diminished sperm membrane fluidity

Dark spots or hyperpigmentation, including those left behind after acne heals (called post-inflammatory hyperpigmentation), are caused by excess melanin