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Purinergic signaling has been shown to regulate physiological processes in kidney such as water and sodium homeostasis, renal blood flow autoregulation, tubular and glomerular functions
But if we had been born, let's say somebody was supposed to be normal weight 100 years ago, fast forward to right now
I do my own
Takahashi Y, Nomoto H, Yokoyama H et al (2023) Improvement of glycaemic control and treatment satisfaction by switching from liraglutide or dulaglutide to subcutaneous semaglutide in patients with type 2 diabetes: a multicentre, prospective, randomized, open-label, parallel-group comparison study (SWITCH-SEMA 1 study)
The highest dose, 15mg, is often considered the maintenance dose for individuals who respond well and tolerate the treatment
