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GLP-1 stands for glucagon-like peptide-1 which is a key hormone that helps the body regulate blood sugar levels, insulin levels, and metabolism
A Phase 1a, blinded, placebo-controlled, randomized, single- and multiple-ascending-dose study was done to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple doses of orforglipron
Qian F, Mathias N, Moench P, Chi C, Desikan S, Hussain M, et al
As our understanding of the heterogenous factors driving OSA advances, novel therapies targeting specific physiological traitssuch as arousal threshold, ventilatory instability, and upper airway muscle responsivenessare being actively explored, with a promise to expand our therapeutic arsenal
