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32,33 Moreover, immune checkpoint upregulation (PD-1, CTLA-4, TIGIT, LAG-3) and suppressive signaling cascades such as PTEN lossPI3K/AKT hyperactivation exacerbate T-cell dysfunction and resistance to ICIs
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He et al., 2017
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The evidence for the preventive effect of MT on diabetes in in vivo models, as demonstrated under various experimental conditions, indicates that Zn pretreatment (e.g., i.p
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