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In our analysis of clinical studies, we found evidence that people using GLP-1 drugs do not experience higher overall cancer rates compared with non-users
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The A53T mutation in the -synuclein gene ( SNCA A53T , or A53T) is one of the key missense gene mutations linked to early onset familial PD, as the mutated -synuclein variant is prone to self-aggregation (12)
173 At the molecular level, gene modulation techniques, including siRNA- and shRNA-mediated silencing of efflux transporter genes (e.g., ABCB1, ABCG2), as well as CRISPR/Cas9-based gene editing, have successfully resensitized tumor cells to chemotherapy in preclinical models
TNF-, IL-1 and IL-6 blockade and angiogenesis inhibition are also employed clinically due to their roles in the pathogenesis of RA (77)
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