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NOCA4 attaches to ferritin and is destroyed by ferritin phagocytosis (76), eventually releasing free iron to participate in the Fenton reaction, which generates ROS and increases the accumulation of intracellular lipid peroxides (LPOs) and ferroptosis (77) ( Figure 2 )

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Metabolite channeling: a phosphorylcreatine shuttle to mediate high energy phosphate transport between sperm mitochondrion and tail

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