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In individuals with primary coenzyme Q 10 deficiency, early treatment with high-dose coenzyme Q 10 supplementation (1030 mg/kg/day in children and 1.23.0 g/day in adults) may improve the pathological phenotype, yet the effectiveness depends on the type of mutations affecting the coenzyme Q 10 biosynthetic pathway (1, 26)
Seahorse analysis This analysis measures real-time changes in cellular metabolism and has been applied to study S
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Strobel M, Tinz J, Biesalski HK
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