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In fact, most people who take semaglutide do experience side effects, but they are usually mild to moderate in severity
It is a recombinant form of the peptide exendin-4, which is a GLP-1 receptor agonist with a 53% similarity to the gastrointestinal hormone GLP-1 and it is resistant to DPP-4 inactivation with a 140-minute half-life after subcutaneous administration allowing therapy by a twice daily administration [36]
Key Takeaway Semaglutide works best when injected into subcutaneous fat
Tirzepatide induced significant improvements in estradiol, testosterone, LH, FSH, and LH/FSH ratio
While not everyone who takes GLP-1s will have side effects, some will, and they can range from mild to life-threatening
