4 Discussion This study demonstrates how C-terminal acylation of exendin-4 affects several GLP-1R pharmacological properties that are relevant to its therapeutic effect
Data on height, weight, body mass index (BMI), fasting glucose level, estimated glomerular filtration rate (eGFR), smoking status (never, ex-, and current smoker), and alcohol consumption (times per week) were extracted from the results of the national health screening examination conducted closest to the index date
Nguyen NH, Ohno-Machado L, Sandborn WJ, Singh S
One in five (18%) adults now report having ever taken a GLP-1 agonist, including 12% who say they are currently taking this type of medication (a 6 percentage point increase from 18 months ago)
doi: 10.2337/db14-0242 68 BaggerJIHolstJJHartmannBAndersenBKnopFKVilsbollT