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Moreover, intra-articular injection of monoiodoacetate (MIA) induces loss of articular cartilage with subchondral bone lesions that mimic those of human OA and This model offers a rapid and minimally invasive method to reproduce OA-like lesions in a rodent species [13]
Due to the potential of GLP-1R antagonists to modulate T-cell regulation and the evidence that enhancing T-cell infiltration can effectively transform cold tumors into hot tumors (2729), it is plausible that combining GLP-1R antagonists with ICIs may synergistically modulate T-cell-mediated immune sensitivity to improve tumor treatment outcomes
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Adderall, being a stimulant, could potentially alter glycemic control in diabetic patients
One of the most promising options for weight loss is GLP-1, originally developed for type 2 diabetes but now gaining attention for its potential in nondiabetic patients
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