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Amgen's MariTide, which combines GLP-1 agonism with GIP antagonism, was specifically designed based on genetic evidence suggesting this combination could reduce nausea while maintaining weight loss efficacy [44]
Despite overlapping benefits, growing evidence suggests that these agents have distinct and complementary roles in clinical practice
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BMC Bioinformatics
Back Zander, M, Madsbad, S, Madsen, JL, Holst, JJ (9 March 2002) 'Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study', The Lancet , 359/9309, 824-30
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