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Only medicines have to be proven safe before being released into the market, and herbal products do not fall under that category

Similarly, in an article published in Muscle and Fitness, glutathione combined with L-citrulline boosted nitric oxide production (NO) better than placebo or L-citrulline alone.20 Nitric oxide is well known to dilate blood vessels improving blood flow and oxygen delivery to muscles and tissues

Your body produces it naturally, and its found in your blood and tissues