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The benefits
Among GLP-1 RA users, dulaglutide was the most frequently prescribed agent (60.8%), followed by semaglutide (31.1%), tirzepatide (6.8%), and liraglutide (1.4%)
The peptides under investigation, include: Nle-AngIV (Nle-Tyr-Ile-His-Pro-Phe) and its analogs such as D-Nle-YIH, acetyl-NleYIH, -amino butyric acid-YIH, NleYI-amide, and the primary focus, N-hexanoic-Tyr-Ile-(6) aminohexanoic amide (Dihexa)
Topical and cosmetic application in humans is the best-supported use, with controlled dermatological studies showing measurable effects on skin parameters Grade B
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