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TRULICITY is contraindicated in patients with a personal or family history of MTC and in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
For example, individuals exposed to ES exhibit an increased mitochondrial DNA copy number content in leukocytes [193] and in saliva [194] indicating that this effect might be widespread throughout the body and have its origin in childhood
It would be great to undertake studies with the newer dual agonists and polyagonists also in rare obesity syndromes such as AS, Prader-Willi syndrome, and Bardet-Biedl syndrome (just to name a few) as the clinical need for effective obesity/hyperphagia therapies in these patients is especially high, says Scherer
But patience is key
IntHout J, Ioannidis JP, Borm GF
