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GLP-1 receptor agonists and SGLT2 inhibitors: a couple at last
This ubiquitous protease is expressed in several tissues, including pancreatic -cells, and cleaves the amino-terminal dipeptide at the penultimate position with either L-proline or L-alanine (GLP-1), limiting the clinical utility of GLP-1 in T2DM patients, particularly its insulinotropic actions (Saini et al., 2023)
Let the peptide absorb naturally
Two regulatory bodies are relevant here: The Medicines and Healthcare products Regulatory Agency (MHRA) oversees the regulation of herbal medicines through the Traditional Herbal Registration (THR) scheme
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