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Ethics declarations Conflict of Interest Swarna Khare, Beatrice Osumili, and Nele Debackere are employees and shareholders of Eli Lilly and Company
Researchers have successfully detected the presence of BRP in human cerebrospinal fluid samples and mouse brain tissues, suggesting that this molecule may serve as an important signaling mediator within the central nervous system, participating in the regulatory network of various physiological functions
Semaglutide and orforglipron activate only the GLP-1 receptor, producing appetite suppression through hypothalamic signaling, delayed gastric emptying, and enhanced satiety
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