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Lets start with the place where GLP-1 is produced, in the intestines we have what are called enteroendocrine cells, specifically called L-cells

[1] This distinct localization pattern implies that organs primarily involved in metabolic and reproductive functions might have different abilities to absorb or retain IGF-1 LR3 compared to IGF-1

This function is important for cardiovascular health and, in men, can improve erectile function

Their metabolic health markers, such as blood sugar and cholesterol, also returned to levels similar to those before treatment.(3) Another drawback to taking GLP-1 medications is that while they promote weight loss, recently published research shows that approximately 15% to 60% of the loss comes from lean mass.(5, 6) This is very concerning, because preserving muscle mass is crucial for maintaining metabolic rate, overall health, and functionality as we age.(7) The Potential Solution: A Ketogenic Lifestyle A paper by researchers at Virta Health, published in February 2024, suggests that a ketogenic diet may help people maintain their weight loss after transitioning off GLP-1 medications.(8) The study compared two groups of type 2 diabetes patients following a ketogenic diet: one group continued GLP-1 therapy, and the other group stopped the medication

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