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Common GLP-1 agonists include: Semaglutide (Ozempic, Wegovy) Liraglutide (Victoza, Saxenda) Dulaglutide (Trulicity) Tirzepatide (Zepbound) While initially used for diabetes management, studies showed that GLP-1 agonists also contribute significantly to weight loss, leading to their approval for obesity treatment as well

Liraglutide showed greater reduction systolic blood pressure over diastolic in a 14 week study systolic blood pressure decreased by -5.2 mm Hg to -7.2 mm Hg compared to placebo with no difference in diastolic blood pressure

GLP-1 Receptor expression within the human heart

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Tang A, Desai A, Hamilton G, et al