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The hydrophilic head of the lipid molecule can be classified as anionic, cationic, and neutral based on their respective charges (Fig
Further studies are needed to confirm the actual benefit of this molecule on metabolic liver diseases and define the best route of administration and the most appropriate dosage, allowing its use in clinical practice
Loss of intracellular GSH is likely multifactorial and includes generation of high levels of hydroperoxy-phospholipids (which directly or indirectly oxidize GSH and limit GSSG recycling by reductases) as well as active export of GSSG generated by high GPX4 activity (7, 8, 21)
We typically recommend baseline lab work including IGF 1 levels, thyroid panel, and metabolic markers