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Potential areas of expansion include: Cardiovascular outcomes: A dedicated CVOT, if not already required as a post-marketing commitment, would evaluate whether orforglipron reduces MACE in patients with established cardiovascular disease or high cardiovascular risk, following the precedent set by the SELECT trial for semaglutide
Its trickier to hit that 75-plus grams of protein recommendation, but with some planning, the experts say its doable
Because acid reflux is one of the most frequently reported side effects of tirzepatide, many patients look to omeprazole as a logical solution for relief
Potential side effects per NativePath's published FAQ: Temporary water retention, upset stomach, muscle cramps, nausea, diarrhea, and dehydration if fluid intake is insufficient
There was no significant change in the estimated glomerular filtration rate after tirzepatide use with a baseline estimated glomerular filtration rate of 57.92 20.17 to 56.18 20.32 mL/min per 1.73 m 2 (p=0.08)
