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Not approved for human consumption

A small but significant percentage of users, estimated at less than 2% in clinical trials but potentially higher in real-world use, develop gastroparesis symptoms that persist even after stopping the medication

[12] Post-marketing surveillance data from the FDA Adverse Event Reporting System (FAERS) indicate that serious hepatic adverse events with semaglutide are rare, though such spontaneous reporting systems have inherent limitations and cannot establish true incidence or definitive causality

Systematic optimization of interface interactions increases the thermostability of a multimeric enzyme