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A key supporting study was retracted due to data fabrication, and the related prodrug fosgonimeton saw adverse events in clinical trials

Nevertheless, their combined inhibition leads to synthetic lethality

Preventive effects of fructose and N-acetyl-L-cysteine against cytotoxicity induced by the psychoactive compounds N-methyl-5-(2-aminopropyl)benzofuran and 3,4-methylenedioxy-N-methamphetamine in isolated rat hepatocytes