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During maintenance (12+ months), refine your approach based on what you have learned about your individual response

The absolute risk increase for diabetic retinopathy complications was greater among patients with a history of diabetic retinopathy at baseline (semaglutide 8.2%, placebo 5.2%) than among patients without a known history of diabetic retinopathy (semaglutide 0.7%, placebo 0.4%)

Pain levels during daily activities decrease

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Statistical analysis The results obtained were subjected to the analysis of variance using the Statgraphics XVII program