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This dual effect poses a significant challenge in liver cancer therapy, highlighting the need for combinatory approaches that can target senescent cells to improve treatment outcomes 5

Conducted at the Fondazione IRCCS Ca Granda Policlinico of Milan, this prospective case series included 52 infertile women who followed a structured VLCKD using medical meal replacements and controlled supplementation for 3 months, followed by a gradual transition to a Mediterranean-style diet

Oxidative stress-induced premature senescence and aggravated denervated skeletal muscular atrophy by regulating progerin-p53 interaction Skelet Muscle 12 19 103 YanY.LiM.LinJ.JiY.WangK.YanD.et al (2022)

This creates true pathway synergy

The phrase exploded on TikTok and YouTube in early 2026