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Ethics declarations Ethics approval and consent to participate The study protocol was conducted according to the guidelines contained within the Declaration of Helsinki and was approved by the ethics committees of Yokohama City University and Kyoto Prefectural University

Yuan, S

Human studies conducted to date generally involve small sample sizes, heterogeneous dosing regimens, and relatively short intervention periods, restricting the ability to draw robust conclusions regarding efficacy, optimal dosage, and treatment duration

Long-Term Safety and Toxicity Animal studies have not consistently shown major toxicity signals, which is one reason interest in BPC 157 has continued

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