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A resting heart rate consistently above 100 bpm or blood pressure consistently above 140/90 should prompt immediate clinical reassessment
Front Endocrinol (Lausanne) 13:971249, 2022
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This requires recalculating your dose in units, because the same milligram dose requires a different volume at each concentration
Whether retatrutide has the same effect isnt yet documented in detail, but it slows gastric emptying in the same way, so the issue likely applies
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