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These results suggested that keloid fibroblasts underwent pro-senescence regulation earlier compared with normal skin fibroblasts via p53-pS15 under serum limitation stimulus, and p53-pS15 and FOXO4 translocated from the nucleus to the cytoplasm during FOXO4-DRI treatment
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In Eli Lillys SURPASS and SURMOUNT studies, patients lost up to 22% of their body weight over 72 weeks far surpassing results seen with semaglutide
Interestingly, high-intensity exercise might reverse some aging-related cardiovascular issues by improving antioxidant capacity and reducing oxidative stress
doi:10.1016/j.freeradbiomed.2008.10.040 Tsai CC, Chen HS, Chen SL, Ho YP, Ho KY, Wu YM, Hung CC (2005) Lipid peroxidation: a possible role in the induction and progression of chronic periodontitis
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