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2025 Exhibit 114: Express Scripts, Annual Prescription Claims, by Channel, 2019 to 2025 Exhibit 115: Plan Sponsors Perception of PBM Transparency, by PBM Size, 2025 Exhibit 116: PBM-Affiliated Purchasing Groups and Participation, 2026 Exhibit 117: Largest Pharmacy Services Administrative Organizations, by Membership and Ownership, 2025 Exhibit 118: Key Components of PBM Compensation Exhibit 119: Share of Plans Using Various Compensation Elements in PBM Contracts, by Type of Plan Sponsor, 2023 Exhibit 120: Imatinib Mesylate, Fee-for-Service and Managed Medicaid Spreads, 2017 to 2024 Exhibit 121: Top Three PBMs, Sources of Gross Profit, 2012 to 2025 Exhibit 122: Common Pharmacy Benefit Plan Designs Exhibit 123: Share of Employees Covered by a High-Deductible Health Plan, 2006 to 2025 Exhibit 124: Distribution of Cost Sharing Formulas for Prescription Drug Benefits in Employer-Sponsored Plans, by Plan Type, 2025 Exhibit 125: Type of Cost Sharing for Prescription Drug Benefits, Employer-Sponsored Plans Without High Deductibles, by Benefit Tier, 2025 Exhibit 126: Type of Cost Sharing for Prescription Drug Benefits, Employer-Sponsored Plans with High Deductibles, by Benefit Tier, 2025 Exhibit 127: Average Cost Sharing by Prescription Drug Tier, Employer-Sponsored Plans, 2025 Exhibit 128: Number of Specialty Drug Cost-Sharing Tiers, by Type of Plan Sponsor, 2024 Exhibit 129: Distribution of Coinsurance Structures for Prescription Drug Benefits, Employer-Sponsored Plans, Fourth and Specialty Tiers, 2025 Exhibit 130: Percentage of Covered Workers with No Prescription Drug Coverage Before Annual Deductible, by Plan Type, 2020 vs

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With the availability of multiple drug therapies demonstrating promising efficacy, we expect market competition to produce downward pressure on prices, most likely in the form of rebates for GLP-1s

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