Coagonistas GLP-1/glucagn El desarrollo de estas formulaciones unimoleculares con efecto sobre los receptores de GLP-1 y glucagn aporta potenciacin del efecto anorexiante de GLP-1, efecto lipoltico e inhibidor de la lipognesis (tabla 2), particularmente a nivel heptico, y accin termognica, facilitando la reduccin ponderal y el tratamiento de MASLD1,5,35
C., Primavera, A
Microbiota-based interventions to enhance GLP-1 RA efficacy (probiotics, prebiotics, postbiotics) Given the bidirectional interplay between GLP-1 RAs and the gut microbiota, increasing attention has been directed toward microbiota-targeted strategies to address key clinical challenges, such as inter-individual response variability and substantial weight regain after treatment discontinuation
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