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How to Self-Inject Ozempic: Step-by-Step Semaglutide Injection Technique At a glance Drug / semaglutide (Ozempic), manufactured by Novo Nordisk Route / subcutaneous injection, once weekly on the same day each week Dose range / 0.25 mg (starting), 0.5 mg, 1 mg, or 2 mg maintenance Pen types / Ozempic 2 mg pen (delivers 0.25 or 0.5 mg doses) and Ozempic 8 mg pen (delivers 1 or 2 mg doses) Needle gauge / NovoFine Plus 32G x 4 mm, one per injection Injection sites / abdomen (2 inches from navel), front of thigh, upper arm Hold time / keep needle in skin for 6 seconds after pressing dose button Storage / unopened pens refrigerated at 36 to 46F
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