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2-HG is taken up by CD8+ T cells, where it destabilizes HIF-1 and acts as an inhibitor of LDH, resulting in reduced chemotaxis, cytotoxic activity and production of IFN- (172174)
Diabetes Care 2004
This statistic reflects both a higher age-adjusted incidence of AD and longer life expectancy among women (Report, 2024)
Un estudio en personas con prediabetes mostr que 320 mg diarios de antocianinas durante 24 semanas mejoraban la sensibilidad a la insulina en un 22% y reducan significativamente el riesgo de progresin a diabetes tipo 2
doi: 10.1038/s41380-023-02061-8 286 QuekH.Cun-LpezC.StewartR.CollettiT.NotaroA.NguyenT
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